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Mouse models of human TB pathology: roles in the analysis of necrosis and the development of host-directed therapies
A key aspect of TB pathogenesis that maintains Mycobacterium tuberculosis in the human population is the ability to cause necrosis in pulmonary lesions. As co-evolution shaped M. tuberculosis (M.tb) and human responses, the complete TB disease profile and lesion manifestation are not fully reproduce...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Berlin Heidelberg
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779126/ https://www.ncbi.nlm.nih.gov/pubmed/26542392 http://dx.doi.org/10.1007/s00281-015-0538-9 |