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Human Proteomic Variation Revealed by Combining RNA-Seq Proteogenomics and Global Post-Translational Modification (G-PTM) Search Strategy

[Image: see text] Mass-spectrometry-based proteomic analysis underestimates proteomic variation due to the absence of variant peptides and posttranslational modifications (PTMs) from standard protein databases. Each individual carries thousands of missense mutations that lead to single amino acid va...

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Detalles Bibliográficos
Autores principales:	Cesnik, Anthony J., Shortreed, Michael R., Sheynkman, Gloria M., Frey, Brian L., Smith, Lloyd M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2015
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779408/ https://www.ncbi.nlm.nih.gov/pubmed/26704769 http://dx.doi.org/10.1021/acs.jproteome.5b00817

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