Design and Microwave Assisted Synthesis of Coumarin Derivatives as PDE Inhibitors

Coumarins appended to benzimidazole through pyrazole are designed and synthesized using microwave irradiation. These compounds were analyzed for phosphodiesterase (PDE) inhibition indirectly by motility pattern in human spermatozoa. Some of the synthesized compounds, namely, 5d, 5e, 5f, 5g, 5h, and...

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Detalles Bibliográficos
Autores principales: Kumbar, Mahadev N., Kamble, Ravindra R., Kamble, Atulkumar A., Salian, Sujith Raj, Kumari, Sandhya, Nair, Ramya, Kalthur, Guruprasad, Adiga, Satish Kumar, Prasad, D. Jagadeesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779523/
https://www.ncbi.nlm.nih.gov/pubmed/26998358
http://dx.doi.org/10.1155/2016/9890630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779523/
https://www.ncbi.nlm.nih.gov/pubmed/26998358
http://dx.doi.org/10.1155/2016/9890630

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