Reversibility of β-Cell-Specific Transcript Factors Expression by Long-Term Caloric Restriction in db/db Mouse

Type 2 diabetes (T2D) is characterized by β-cell dedifferentiation, but underlying mechanisms remain unclear. The purpose of the current study was to explore the mechanisms of β-cell dedifferentiation with and without long-term control of calorie intake. We used a diabetes mouse model (db/db) to ana...

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Detalles Bibliográficos
Autores principales: Sheng, Chunjun, Li, Feng, Lin, Ziwei, Zhang, Manna, Yang, Peng, Bu, Le, Sheng, Hui, Li, Hong, Qu, Shen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779534/
https://www.ncbi.nlm.nih.gov/pubmed/26998492
http://dx.doi.org/10.1155/2016/6035046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779534/
https://www.ncbi.nlm.nih.gov/pubmed/26998492
http://dx.doi.org/10.1155/2016/6035046

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