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Rare MLL-ELL fusion transcripts in childhood acute myeloid leukemia—association with young age and myeloid sarcomas?
BACKGROUND: The chromosomal translocation t(11;19)(q23;p13) with a breakpoint within subband 19p13.1 is found mainly in acute myeloid leukemia (AML) and results in the MLL-ELL fusion gene. Variations in the structure of MLL-ELL seem to influence the leukemogenic potency of the fusion in vivo and may...
Autores principales: | Panagopoulos, Ioannis, Gorunova, Ludmila, Kerndrup, Gitte, Spetalen, Signe, Tierens, Anne, Osnes, Liv T. N., Andersen, Kristin, Müller, Lil-Sofie Ording, Hellebostad, Marit, Zeller, Bernward, Heim, Sverre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779576/ https://www.ncbi.nlm.nih.gov/pubmed/26949571 http://dx.doi.org/10.1186/s40164-016-0037-2 |
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