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Angiomyolipoma and Malignant PEComa: Discussion of Two Rare Adrenal Tumors
Angiomyolipoma and PEComa are rare tumors descending from perivascular epithelial cells (PECs), with distinctive IHC, morphological, and ultrastructural features. The kidney is the most frequent site of origin, but not the only one; however, adrenal gland angiomyolipomas are extremely rare. We descr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779821/ https://www.ncbi.nlm.nih.gov/pubmed/26998374 http://dx.doi.org/10.1155/2016/5204092 |
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author | Kwazneski II, Douglas Merrill, Megan Young, Jessica Sell, Harry |
author_facet | Kwazneski II, Douglas Merrill, Megan Young, Jessica Sell, Harry |
author_sort | Kwazneski II, Douglas |
collection | PubMed |
description | Angiomyolipoma and PEComa are rare tumors descending from perivascular epithelial cells (PECs), with distinctive IHC, morphological, and ultrastructural features. The kidney is the most frequent site of origin, but not the only one; however, adrenal gland angiomyolipomas are extremely rare. We describe two cases being found in the adrenal glands. Given the paucity of literature on the subject, more information on this disease is necessary for diagnosis and treatment. Here, we describe two complete case reports, from presentation to treatment and follow-up, along with imaging and microscopic pathology samples, and provide a comprehensive review as to the history and current literature available regarding these extremely rare tumors. |
format | Online Article Text |
id | pubmed-4779821 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-47798212016-03-20 Angiomyolipoma and Malignant PEComa: Discussion of Two Rare Adrenal Tumors Kwazneski II, Douglas Merrill, Megan Young, Jessica Sell, Harry Case Rep Oncol Med Case Report Angiomyolipoma and PEComa are rare tumors descending from perivascular epithelial cells (PECs), with distinctive IHC, morphological, and ultrastructural features. The kidney is the most frequent site of origin, but not the only one; however, adrenal gland angiomyolipomas are extremely rare. We describe two cases being found in the adrenal glands. Given the paucity of literature on the subject, more information on this disease is necessary for diagnosis and treatment. Here, we describe two complete case reports, from presentation to treatment and follow-up, along with imaging and microscopic pathology samples, and provide a comprehensive review as to the history and current literature available regarding these extremely rare tumors. Hindawi Publishing Corporation 2016 2016-02-22 /pmc/articles/PMC4779821/ /pubmed/26998374 http://dx.doi.org/10.1155/2016/5204092 Text en Copyright © 2016 Douglas Kwazneski II et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Kwazneski II, Douglas Merrill, Megan Young, Jessica Sell, Harry Angiomyolipoma and Malignant PEComa: Discussion of Two Rare Adrenal Tumors |
title | Angiomyolipoma and Malignant PEComa: Discussion of Two Rare Adrenal Tumors |
title_full | Angiomyolipoma and Malignant PEComa: Discussion of Two Rare Adrenal Tumors |
title_fullStr | Angiomyolipoma and Malignant PEComa: Discussion of Two Rare Adrenal Tumors |
title_full_unstemmed | Angiomyolipoma and Malignant PEComa: Discussion of Two Rare Adrenal Tumors |
title_short | Angiomyolipoma and Malignant PEComa: Discussion of Two Rare Adrenal Tumors |
title_sort | angiomyolipoma and malignant pecoma: discussion of two rare adrenal tumors |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779821/ https://www.ncbi.nlm.nih.gov/pubmed/26998374 http://dx.doi.org/10.1155/2016/5204092 |
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