Cargando…
Increasing TRPV4 expression restores flow-induced dilation impaired in mesenteric arteries with aging
The flow-stimulated intracellular Ca(2+) concentration ([Ca(2+)](i)) rise in endothelial cells is an important early event leading to flow-induced blood vessel dilation. Transient receptor potential vanilloid subtype 4 (TRPV4), a Ca(2+)-permeable cation channel, facilitates the flow-stimulated [Ca(2...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780030/ https://www.ncbi.nlm.nih.gov/pubmed/26947561 http://dx.doi.org/10.1038/srep22780 |