NECAB3 Promotes Activation of Hypoxia-inducible factor-1 during Normoxia and Enhances Tumourigenicity of Cancer Cells

Unlike most cells, cancer cells activate hypoxia inducible factor-1 (HIF-1) to use glycolysis even at normal oxygen levels, or normoxia. Therefore, HIF-1 is an attractive target in cancer therapy. However, the regulation of HIF-1 during normoxia is not well characterised, although Mint3 was recently...

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Detalles Bibliográficos
Autores principales: Nakaoka, Hiroki J., Hara, Toshiro, Yoshino, Seiko, Kanamori, Akane, Matsui, Yusuke, Shimamura, Teppei, Sato, Hiroshi, Murakami, Yoshinori, Seiki, Motoharu, Sakamoto, Takeharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780031/
https://www.ncbi.nlm.nih.gov/pubmed/26948053
http://dx.doi.org/10.1038/srep22784

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