Challenges and advances in optimizing liver allografts from donation after circulatory death donors

In recent years, there has been a shift in the donor demographics with an increase in donation after circulatory death (DCD). Livers obtained from DCD donors are known to have poorer outcomes when compared to donors after brainstem death and currently only a small proportion of DCD livers are used....

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Detalles Bibliográficos
Autores principales: Sutherland, Andrew Ian, Oniscu, Gabriel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780154/
https://www.ncbi.nlm.nih.gov/pubmed/27003962
http://dx.doi.org/10.4103/0976-9668.175017
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author Sutherland, Andrew Ian
Oniscu, Gabriel C.
author_facet Sutherland, Andrew Ian
Oniscu, Gabriel C.
author_sort Sutherland, Andrew Ian
collection PubMed
description In recent years, there has been a shift in the donor demographics with an increase in donation after circulatory death (DCD). Livers obtained from DCD donors are known to have poorer outcomes when compared to donors after brainstem death and currently only a small proportion of DCD livers are used. This review outlines the recent technological developments in liver DCD donation, including clinical studies using normothermic regional perfusion and extracorporal machine perfusion of livers from DCD donors.
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spelling pubmed-47801542016-03-21 Challenges and advances in optimizing liver allografts from donation after circulatory death donors Sutherland, Andrew Ian Oniscu, Gabriel C. J Nat Sci Biol Med Review Article In recent years, there has been a shift in the donor demographics with an increase in donation after circulatory death (DCD). Livers obtained from DCD donors are known to have poorer outcomes when compared to donors after brainstem death and currently only a small proportion of DCD livers are used. This review outlines the recent technological developments in liver DCD donation, including clinical studies using normothermic regional perfusion and extracorporal machine perfusion of livers from DCD donors. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4780154/ /pubmed/27003962 http://dx.doi.org/10.4103/0976-9668.175017 Text en Copyright: © 2016 Journal of Natural Science, Biology and Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Review Article
Sutherland, Andrew Ian
Oniscu, Gabriel C.
Challenges and advances in optimizing liver allografts from donation after circulatory death donors
title Challenges and advances in optimizing liver allografts from donation after circulatory death donors
title_full Challenges and advances in optimizing liver allografts from donation after circulatory death donors
title_fullStr Challenges and advances in optimizing liver allografts from donation after circulatory death donors
title_full_unstemmed Challenges and advances in optimizing liver allografts from donation after circulatory death donors
title_short Challenges and advances in optimizing liver allografts from donation after circulatory death donors
title_sort challenges and advances in optimizing liver allografts from donation after circulatory death donors
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780154/
https://www.ncbi.nlm.nih.gov/pubmed/27003962
http://dx.doi.org/10.4103/0976-9668.175017
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