A covalent and cleavable antibody-DNA conjugation strategy for sensitive protein detection via immuno-PCR

Immuno-PCR combines specific antibody-based protein detection with the sensitivity of PCR-based quantification through the use of antibody-DNA conjugates. The production of such conjugates depends on the availability of quick and efficient conjugation strategies for the two biomolecules. Here, we pr...

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Detalles Bibliográficos
Autores principales: van Buggenum, Jessie A. G. L., Gerlach, Jan P., Eising, Selma, Schoonen, Lise, van Eijl, Roderick A. P. M., Tanis, Sabine E. J., Hogeweg, Mark, Hubner, Nina C., van Hest, Jan C., Bonger, Kimberly M., Mulder, Klaas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780193/
https://www.ncbi.nlm.nih.gov/pubmed/26947912
http://dx.doi.org/10.1038/srep22675

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