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Serum Klotho Levels in Trained Athletes

BACKGROUND: Klotho is an anti-aging protein that is predominantly secreted by the kidneys. OBJECTIVES: The aim of the study was to measure and compare the circulating Klotho levels in the serum of trained athletes and in healthy, non-athlete controls. MATERIALS AND METHODS: Thirty trained football p...

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Detalles Bibliográficos
Autores principales: Mostafidi, Elmira, Moeen, Akbar, Nasri, Hamid, Ghorbani Hagjo, Amir, Ardalan, Mohammadreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780197/
https://www.ncbi.nlm.nih.gov/pubmed/26981496
http://dx.doi.org/10.5812/numonthly.30245
Descripción
Sumario:BACKGROUND: Klotho is an anti-aging protein that is predominantly secreted by the kidneys. OBJECTIVES: The aim of the study was to measure and compare the circulating Klotho levels in the serum of trained athletes and in healthy, non-athlete controls. MATERIALS AND METHODS: Thirty trained football players were enrolled and their serum Klotho levels were measured the morning after their last evening exercise training. RESULTS: The plasma free Klotho concentration was significantly higher in the athlete group (3.375 ± 1.48 ng/mL) compared to the non-athletes (1.39 ± 0.43 ng/mL) (P < 0.05). Serum levels of cholesterol, triglycerides, calcium, and phosphorus were not significantly different between the two groups. CONCLUSIONS: Regular aerobic exercise could increase plasma Klotho levels, and this could be an explanation for exercise-related anti-aging effects.