Cargando…

Da0324, an inhibitor of nuclear factor-κB activation, demonstrates selective antitumor activity on human gastric cancer cells

BACKGROUND: The transcription factor nuclear factor-κB (NF-κB) is constitutively activated in a variety of human cancers, including gastric cancer. NF-κB inhibitors that selectively kill cancer cells are urgently needed for cancer treatment. Curcumin is a potent inhibitor of NF-κB activation. Unfort...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jin, Rong, Xia, Yiqun, Chen, Qiuxiang, Li, Wulan, Chen, Dahui, Ye, Hui, Zhao, Chengguang, Du, Xiaojing, Shi, Dengjian, Wu, Jianzhang, Liang, Guang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780725/ https://www.ncbi.nlm.nih.gov/pubmed/27042000 http://dx.doi.org/10.2147/DDDT.S90081

Ejemplares similares

The Curcumin Analog Da0324 Inhibits the Proliferation of Gastric Cancer Cells via HOTAIRM1/miR-29b-1-5p/PHLPP1 Axis
por: Xu, Fanfan, et al.
Publicado: (2022)

PA03.24. Assessment of Ayurvedic treatment on Aphonia as a complication of Thyroidectomy.
por: Phatak, Shruti
Publicado: (2013)

Network analysis identifies Rv0324 and Rv0880 as regulators of bedaquiline tolerance in Mycobacterium tuberculosis
por: Peterson, Eliza J.R., et al.
Publicado: (2016)

Flubendazole demonstrates valid antitumor effects by inhibiting STAT3 and activating autophagy
por: Lin, Shichong, et al.
Publicado: (2019)

BB0324 and BB0028 are constituents of the Borrelia burgdorferi β-barrel assembly machine (BAM) complex
por: Lenhart, Tiffany R, et al.
Publicado: (2012)

EHMTI-0324. Expression of high-mobility group box 1 in the cerebral cortex after cortical spreading depression
por: Takizawa, T, et al.
Publicado: (2014)

NF-κB-Related Metabolic Gene Signature Predicts the Prognosis and Immunotherapy Response in Gastric Cancer
por: Chen, Qiuxiang, et al.
Publicado: (2022)

Curcumin sensitizes human gastric cancer cells to 5-fluorouracil through inhibition of the NFκB survival-signaling pathway
por: Kang, Yanting, et al.
Publicado: (2016)

Curcumin Analogue CA15 Exhibits Anticancer Effects on HEp-2 Cells via Targeting NF-κB
por: Chen, Jian, et al.
Publicado: (2017)

Corrigendum to “Curcumin Analogue CA15 Exhibits Anticancer Effects on HEp-2 Cells via Targeting NF-κB”
por: Chen, Jian, et al.
Publicado: (2017)

Bioinformatics Analysis Revealing the Correlation between NF-κB Signaling Pathway and Immune Infiltration in Gastric Cancer
por: Chen, Qiuxiang, et al.
Publicado: (2022)

Synthesis and biological evaluation of a novel class of curcumin analogs as anti-inflammatory agents for prevention and treatment of sepsis in mouse model
por: Zhao, Chengguang, et al.
Publicado: (2015)

ARV-825 Demonstrates Antitumor Activity in Gastric Cancer via MYC-Targets and G2M-Checkpoint Signaling Pathways
por: Liao, Xinmei, et al.
Publicado: (2021)

FGF/FGFR-related lncRNAs based classification predicts prognosis and guides therapy in gastric cancer
por: Chen, Qiuxiang, et al.
Publicado: (2022)

Design and Synthesis of Novel Nordihydroguaiaretic Acid (NDGA) Analogues as Potential FGFR1 Kinase Inhibitors With Anti-Gastric Activity and Chemosensitizing Effect
por: Chen, Qian, et al.
Publicado: (2020)

Mycobacterium tuberculosis 10-kDa co-chaperonin regulates the expression levels of receptor activator of nuclear factor-κB ligand and osteoprotegerin in human osteoblasts
por: ZHANG, YUANYU, et al.
Publicado: (2015)

Retigeric Acid B Exhibits Antitumor Activity through Suppression of Nuclear Factor-κB Signaling in Prostate Cancer Cells in Vitro and in Vivo
por: Liu, Yong-Qing, et al.
Publicado: (2012)

Hydrogen Sulfide Demonstrates Promising Antitumor Efficacy in Gastric Carcinoma by Targeting MGAT5()()
por: Wang, Rui, et al.
Publicado: (2018)

Synergistic antitumor activity of rapamycin and EF24 via increasing ROS for the treatment of gastric cancer
por: Chen, Weiqian, et al.
Publicado: (2016)

The Synergistic Antitumor Activity of Chidamide in Combination with Bortezomib on Gastric Cancer
por: Zhang, Wanjun, et al.
Publicado: (2020)

Niclosamide, an old antihelminthic agent, demonstrates antitumor activity by blocking multiple signaling pathways of cancer stem cells
por: Pan, Jing-Xuan, et al.
Publicado: (2012)

Daratumumab-(225)Actinium conjugate demonstrates greatly enhanced antitumor activity against experimental multiple myeloma tumors
por: Dawicki, Wojciech, et al.
Publicado: (2019)

Non-thermal plasma-treated solution demonstrates antitumor activity against pancreatic cancer cells in vitro and in vivo
por: Liedtke, Kim Rouven, et al.
Publicado: (2017)

Ligufalimab, a novel anti-CD47 antibody with no hemagglutination demonstrates both monotherapy and combo antitumor activity
por: Qu, Tailong, et al.
Publicado: (2022)

Inhibition of HDACs-EphA2 Signaling Axis with WW437 Demonstrates Promising Preclinical Antitumor Activity in Breast Cancer
por: Zhang, Tao, et al.
Publicado: (2018)

Losartan Inhibits Nuclear Factor-κB Activation Induced by Small, Dense LDL Cholesterol Particles in Human Umbilical Vein Endothelial Cells()
por: Guo, Gonghui, et al.
Publicado: (2014)

The Antitumor Activities of Marsdenia tenacissima
por: Wang, Xiang, et al.
Publicado: (2018)

Biomarkers for antitumor activity of bevacizumab in gastric cancer models
por: Yamashita-Kashima, Yoriko, et al.
Publicado: (2012)

Chemo-drugs in cell microparticles reset antitumor activity of macrophages by activating lysosomal P450 and nuclear hnRNPA2B1
por: Wei, Keke, et al.
Publicado: (2023)

Antitumor activity of IL-32β through the activation of lymphocytes, and the inactivation of NF-κB and STAT3 signals
por: Yun, H-M, et al.
Publicado: (2013)

Beyond NF-κB activation: nuclear functions of IκB kinase α
por: Huang, Wei-Chien, et al.
Publicado: (2013)

Insights on Antitumor Activity and Mechanism of Natural Benzophenanthridine Alkaloids
por: Peng, Rui, et al.
Publicado: (2023)

EriB targeted inhibition of microglia activity attenuates MPP(+) induced DA neuron injury through the NF-κB signaling pathway
por: Dou, Fangfang, et al.
Publicado: (2018)

ROR activation by Nobiletin enhances antitumor efficacy via suppression of IκB/NF-κB signaling in triple-negative breast cancer
por: Kim, Eunju, et al.
Publicado: (2022)

Demonstration of diamond nuclear spin gyroscope
por: Jarmola, Andrey, et al.
Publicado: (2021)

Anticellular and Antitumor Activity of Duocarmycins, Novel Antitumor Antibiotics
por: Gomi, Katsushige, et al.
Publicado: (1992)

Nuclear factor-κB activation in perihematomal brain tissue correlates with outcome in patients with intracerebral hemorrhage
por: Zhang, Ze-Li, et al.
Publicado: (2015)

The Antitumor Effects of Plasma-Activated Saline on Muscle-Invasive Bladder Cancer Cells In Vitro and In Vivo Demonstrate Its Feasibility as a Potential Therapeutic Approach
por: Zhang, Hao, et al.
Publicado: (2021)

Jianpi Qingchang decoction alleviates ulcerative colitis by inhibiting nuclear factor-κB activation
por: Zheng, Lie, et al.
Publicado: (2017)

Combined inhibition of MEK and nuclear ERK translocation has synergistic antitumor activity in melanoma cells
por: Arafeh, Rand, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_fjei5clvgdqbiegivo1uk48i4n