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Hormesis in Cholestatic Liver Disease; Preconditioning with Low Bile Acid Concentrations Protects against Bile Acid-Induced Toxicity
INTRODUCTION: Cholestasis is characterized by accumulation of bile acids and inflammation, causing hepatocellular damage. Still, liver damage markers are highest in acute cholestasis and drop when this condition becomes chronic, indicating that hepatocytes adapt towards the hostile environment. This...
Autores principales: | Verhaag, Esther M., Buist-Homan, Manon, Koehorst, Martijn, Groen, Albert K., Moshage, Han, Faber, Klaas Nico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780766/ https://www.ncbi.nlm.nih.gov/pubmed/26950211 http://dx.doi.org/10.1371/journal.pone.0149782 |
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