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HBpF-proBDNF: A New Tool for the Analysis of Pro-Brain Derived Neurotrophic Factor Receptor Signaling and Cell Biology

Neurotrophins activate intracellular signaling pathways necessary for neuronal survival, growth and apoptosis. The most abundant neurotrophin in the adult brain, brain-derived neurotrophic factor (BDNF), is first synthesized as a proBDNF precursor and recent studies have demonstrated that proBDNF ca...

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Detalles Bibliográficos
Autores principales: Gaub, Perrine, de Léon, Andrès, Gibon, Julien, Soubannier, Vincent, Dorval, Geneviève, Séguéla, Philippe, Barker, Philip A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780767/
https://www.ncbi.nlm.nih.gov/pubmed/26950209
http://dx.doi.org/10.1371/journal.pone.0150601