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Sequential Extraction of Soluble and Insoluble Alpha-Synuclein from Parkinsonian Brains
Alpha-synuclein (α-syn) protein is abundantly expressed mainly within neurons, and exists in a number of different forms - monomers, tetramers, oligomers and fibrils. During disease, α-syn undergoes conformational changes to form oligomers and high molecular weight aggregates that tend to make the p...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MyJove Corporation
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4781043/ https://www.ncbi.nlm.nih.gov/pubmed/26780369 http://dx.doi.org/10.3791/53415 |