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CDK1-Cyclin B1 Activates RNMT, Coordinating mRNA Cap Methylation with G1 Phase Transcription

The creation of translation-competent mRNA is dependent on RNA polymerase II transcripts being modified by addition of the 7-methylguanosine (m7G) cap. The factors that mediate splicing, nuclear export, and translation initiation are recruited to the transcript via the cap. The cap structure is form...

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Detalles Bibliográficos
Autores principales:	Aregger, Michael, Kaskar, Aneesa, Varshney, Dhaval, Fernandez-Sanchez, Maria Elena, Inesta-Vaquera, Francisco A., Weidlich, Simone, Cowling, Victoria H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4781437/ https://www.ncbi.nlm.nih.gov/pubmed/26942677 http://dx.doi.org/10.1016/j.molcel.2016.02.008

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