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Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes

Enzyme catalysis evolved in an aqueous environment. The influence of solvent dynamics on catalysis is, however, currently poorly understood and usually neglected. The study of water dynamics in enzymes and the associated thermodynamical consequences is highly complex and has involved computer simula...

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Detalles Bibliográficos
Autores principales: Kürten, Charlotte, Syrén, Per-Olof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4781653/
https://www.ncbi.nlm.nih.gov/pubmed/26862836
http://dx.doi.org/10.3791/53168