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Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss

Sudden sensorineural hearing loss (SSHL) is characterized by acute, idiopathic hearing loss. The estimated incidence rate is 5-30 cases per 100,000 people per year. The causes of SSHL and the mechanisms underlying SSHL currently remain unknown. Based on several hypotheses such as a circulatory distu...

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Autores principales: Sekiya, Kenichi, Fukushima, Munehisa, Teismann, Henning, Lagemann, Lothar, Kakigi, Ryusuke, Pantev, Christo, Okamoto, Hidehiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4781698/
https://www.ncbi.nlm.nih.gov/pubmed/26863274
http://dx.doi.org/10.3791/53264
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author Sekiya, Kenichi
Fukushima, Munehisa
Teismann, Henning
Lagemann, Lothar
Kakigi, Ryusuke
Pantev, Christo
Okamoto, Hidehiko
author_facet Sekiya, Kenichi
Fukushima, Munehisa
Teismann, Henning
Lagemann, Lothar
Kakigi, Ryusuke
Pantev, Christo
Okamoto, Hidehiko
author_sort Sekiya, Kenichi
collection PubMed
description Sudden sensorineural hearing loss (SSHL) is characterized by acute, idiopathic hearing loss. The estimated incidence rate is 5-30 cases per 100,000 people per year. The causes of SSHL and the mechanisms underlying SSHL currently remain unknown. Based on several hypotheses such as a circulatory disturbance to the cochlea, viral infection, and autoimmune disease, pharmaco-therapeutic approaches have been applied to treat SSHL patients; however, the efficacy of the standard treatment, corticosteroid therapy, is still under debate. Exposure to intense sounds has been shown to cause permanent damage to the auditory system; however, exposure to a moderate level enriched acoustic environment after noise trauma may reduce hearing impairments. Several neuroimaging studies recently suggested that the onset of SSHL induced maladaptive cortical reorganization in the human auditory cortex, and that the degree of cortical reorganization in the acute SSHL phase negatively correlated with the recovery rate from hearing loss. This article reports the development of a novel neuro-rehabilitation approach for SSHL, "constraint-induced sound therapy (CIST)". The aim of the CIST protocol is to prevent or reduce maladaptive cortical reorganization by using an enriched acoustic environment. The canal of the intact ear of SSHL patients is plugged in order to motivate them to actively use the affected ear and thereby prevent progress of maladaptive cortical reorganization. The affected ear is also exposed to music via a headphone for 6 hr per day during hospitalization. The CIST protocol appears to be a safe, easy, inexpensive, and effective treatment for SSHL.
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spelling pubmed-47816982016-03-09 Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss Sekiya, Kenichi Fukushima, Munehisa Teismann, Henning Lagemann, Lothar Kakigi, Ryusuke Pantev, Christo Okamoto, Hidehiko J Vis Exp Behavior Sudden sensorineural hearing loss (SSHL) is characterized by acute, idiopathic hearing loss. The estimated incidence rate is 5-30 cases per 100,000 people per year. The causes of SSHL and the mechanisms underlying SSHL currently remain unknown. Based on several hypotheses such as a circulatory disturbance to the cochlea, viral infection, and autoimmune disease, pharmaco-therapeutic approaches have been applied to treat SSHL patients; however, the efficacy of the standard treatment, corticosteroid therapy, is still under debate. Exposure to intense sounds has been shown to cause permanent damage to the auditory system; however, exposure to a moderate level enriched acoustic environment after noise trauma may reduce hearing impairments. Several neuroimaging studies recently suggested that the onset of SSHL induced maladaptive cortical reorganization in the human auditory cortex, and that the degree of cortical reorganization in the acute SSHL phase negatively correlated with the recovery rate from hearing loss. This article reports the development of a novel neuro-rehabilitation approach for SSHL, "constraint-induced sound therapy (CIST)". The aim of the CIST protocol is to prevent or reduce maladaptive cortical reorganization by using an enriched acoustic environment. The canal of the intact ear of SSHL patients is plugged in order to motivate them to actively use the affected ear and thereby prevent progress of maladaptive cortical reorganization. The affected ear is also exposed to music via a headphone for 6 hr per day during hospitalization. The CIST protocol appears to be a safe, easy, inexpensive, and effective treatment for SSHL. MyJove Corporation 2016-01-25 /pmc/articles/PMC4781698/ /pubmed/26863274 http://dx.doi.org/10.3791/53264 Text en Copyright © 2016, Journal of Visualized Experiments http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visithttp://creativecommons.org/licenses/by-nc-nd/3.0/
spellingShingle Behavior
Sekiya, Kenichi
Fukushima, Munehisa
Teismann, Henning
Lagemann, Lothar
Kakigi, Ryusuke
Pantev, Christo
Okamoto, Hidehiko
Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
title Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
title_full Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
title_fullStr Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
title_full_unstemmed Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
title_short Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
title_sort neuro-rehabilitation approach for sudden sensorineural hearing loss
topic Behavior
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4781698/
https://www.ncbi.nlm.nih.gov/pubmed/26863274
http://dx.doi.org/10.3791/53264
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