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Pipeline Embolization Device for Large/Giant or Fusiform Aneurysms: An Initial Multi-Center Experience in Korea
PURPOSE: The purpose of this study was to assess the safety and early outcomes of the Pipeline device for large/giant or fusiform aneurysms. MATERIALS AND METHODS: The Pipeline was implanted in a total of 45 patients (mean age, 58 years; M:F=10:35) with 47 large/giant or fusiform aneurysms. We retro...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society of Interventional Neuroradiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4781911/ https://www.ncbi.nlm.nih.gov/pubmed/26958407 http://dx.doi.org/10.5469/neuroint.2016.11.1.10 |
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author | Kim, Byung Moon Shin, Yong Sam Baik, Min Woo Lee, Deok Hee Jeon, Pyoung Baik, Seung Kug Lee, Tae Hong Kang, Dong-Hoon Suh, Sang-il Byun, Jun Soo Jung, Jin-Young Kwon, Kihun Kim, Dong Joon Park, Keun Young Kim, Bum-soo Park, Jung Cheol Kim, Seong Rim Kim, Young Woo Kim, Hoon Jo, Kyungil Yoon, Chang Hyo Kim, Young Soo |
author_facet | Kim, Byung Moon Shin, Yong Sam Baik, Min Woo Lee, Deok Hee Jeon, Pyoung Baik, Seung Kug Lee, Tae Hong Kang, Dong-Hoon Suh, Sang-il Byun, Jun Soo Jung, Jin-Young Kwon, Kihun Kim, Dong Joon Park, Keun Young Kim, Bum-soo Park, Jung Cheol Kim, Seong Rim Kim, Young Woo Kim, Hoon Jo, Kyungil Yoon, Chang Hyo Kim, Young Soo |
author_sort | Kim, Byung Moon |
collection | PubMed |
description | PURPOSE: The purpose of this study was to assess the safety and early outcomes of the Pipeline device for large/giant or fusiform aneurysms. MATERIALS AND METHODS: The Pipeline was implanted in a total of 45 patients (mean age, 58 years; M:F=10:35) with 47 large/giant or fusiform aneurysms. We retrospectively evaluated the characteristics of the treated aneurysms, the periprocedural events, morbidity and mortality, and the early outcomes after Pipeline implantation. RESULTS: The aneurysms were located in the internal carotid artery (ICA) cavernous segment (n=25), ICA intradural segment (n=11), vertebrobasilar trunk (n=8), and middle cerebral artery (n=3). Procedure-related events occurred in 18 cases, consisting of incomplete expansion (n=8), shortening-migration (n=5), transient occlusion of a jailed branch (n=3), and in-stent thrombosis (n=2). Treatment-related morbidity occurred in two patients, but without mortality. Both patients had modified Rankin scale (mRS) scores of 2, but had an improved mRS score of 0 at 1-month follow-up. Of the 19 patients presenting with mass effect, 16 improved but three showed no changes in their presenting symptoms. All patients had excellent outcomes (mRS, 0 or 1) during the follow-up period (median, 6 months; range, 2-30 months). Vascular imaging follow-up (n=31, 65.9%; median, 3 months, range, 1-25 months) showed complete or near occlusion of the aneurysm in 24 patients (77.4%) and decreased sac size in seven patients (22.6%). CONCLUSION: In this initial multicenter study in Korea, the Pipeline seemed to be safe and effective for large/giant or fusiform aneurysms. However, a learning period may be required to alleviate device-related events. |
format | Online Article Text |
id | pubmed-4781911 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Korean Society of Interventional Neuroradiology |
record_format | MEDLINE/PubMed |
spelling | pubmed-47819112016-03-08 Pipeline Embolization Device for Large/Giant or Fusiform Aneurysms: An Initial Multi-Center Experience in Korea Kim, Byung Moon Shin, Yong Sam Baik, Min Woo Lee, Deok Hee Jeon, Pyoung Baik, Seung Kug Lee, Tae Hong Kang, Dong-Hoon Suh, Sang-il Byun, Jun Soo Jung, Jin-Young Kwon, Kihun Kim, Dong Joon Park, Keun Young Kim, Bum-soo Park, Jung Cheol Kim, Seong Rim Kim, Young Woo Kim, Hoon Jo, Kyungil Yoon, Chang Hyo Kim, Young Soo Neurointervention Original Paper PURPOSE: The purpose of this study was to assess the safety and early outcomes of the Pipeline device for large/giant or fusiform aneurysms. MATERIALS AND METHODS: The Pipeline was implanted in a total of 45 patients (mean age, 58 years; M:F=10:35) with 47 large/giant or fusiform aneurysms. We retrospectively evaluated the characteristics of the treated aneurysms, the periprocedural events, morbidity and mortality, and the early outcomes after Pipeline implantation. RESULTS: The aneurysms were located in the internal carotid artery (ICA) cavernous segment (n=25), ICA intradural segment (n=11), vertebrobasilar trunk (n=8), and middle cerebral artery (n=3). Procedure-related events occurred in 18 cases, consisting of incomplete expansion (n=8), shortening-migration (n=5), transient occlusion of a jailed branch (n=3), and in-stent thrombosis (n=2). Treatment-related morbidity occurred in two patients, but without mortality. Both patients had modified Rankin scale (mRS) scores of 2, but had an improved mRS score of 0 at 1-month follow-up. Of the 19 patients presenting with mass effect, 16 improved but three showed no changes in their presenting symptoms. All patients had excellent outcomes (mRS, 0 or 1) during the follow-up period (median, 6 months; range, 2-30 months). Vascular imaging follow-up (n=31, 65.9%; median, 3 months, range, 1-25 months) showed complete or near occlusion of the aneurysm in 24 patients (77.4%) and decreased sac size in seven patients (22.6%). CONCLUSION: In this initial multicenter study in Korea, the Pipeline seemed to be safe and effective for large/giant or fusiform aneurysms. However, a learning period may be required to alleviate device-related events. Korean Society of Interventional Neuroradiology 2016-03 2016-03-03 /pmc/articles/PMC4781911/ /pubmed/26958407 http://dx.doi.org/10.5469/neuroint.2016.11.1.10 Text en Copyright © 2016 Korean Society of Interventional Neuroradiology http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Paper Kim, Byung Moon Shin, Yong Sam Baik, Min Woo Lee, Deok Hee Jeon, Pyoung Baik, Seung Kug Lee, Tae Hong Kang, Dong-Hoon Suh, Sang-il Byun, Jun Soo Jung, Jin-Young Kwon, Kihun Kim, Dong Joon Park, Keun Young Kim, Bum-soo Park, Jung Cheol Kim, Seong Rim Kim, Young Woo Kim, Hoon Jo, Kyungil Yoon, Chang Hyo Kim, Young Soo Pipeline Embolization Device for Large/Giant or Fusiform Aneurysms: An Initial Multi-Center Experience in Korea |
title | Pipeline Embolization Device for Large/Giant or Fusiform Aneurysms: An Initial Multi-Center Experience in Korea |
title_full | Pipeline Embolization Device for Large/Giant or Fusiform Aneurysms: An Initial Multi-Center Experience in Korea |
title_fullStr | Pipeline Embolization Device for Large/Giant or Fusiform Aneurysms: An Initial Multi-Center Experience in Korea |
title_full_unstemmed | Pipeline Embolization Device for Large/Giant or Fusiform Aneurysms: An Initial Multi-Center Experience in Korea |
title_short | Pipeline Embolization Device for Large/Giant or Fusiform Aneurysms: An Initial Multi-Center Experience in Korea |
title_sort | pipeline embolization device for large/giant or fusiform aneurysms: an initial multi-center experience in korea |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4781911/ https://www.ncbi.nlm.nih.gov/pubmed/26958407 http://dx.doi.org/10.5469/neuroint.2016.11.1.10 |
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