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Dataset of liver proteins changed in eu- and hypothyroid female rats upon in vivo exposure to hexabromocyclododecane (HBCD)
Female Wistar rats with different thyroid status (eu-, hypothyroid) were exposed to 0, 3 or 30 mg/kg body weight of the flame retardant HBCD for 7 days. Changes in protein patterns obtained by 2D-DIGE were evaluated, and different animal groups compared taking into account their exposure and thyroid...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4781926/ https://www.ncbi.nlm.nih.gov/pubmed/26977443 http://dx.doi.org/10.1016/j.dib.2016.02.047 |
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author | Miller, I. Serchi, T. Cambier, S. Diepenbroek, C. Renaut, J. van den Berg, J.H.J. Kwadijk, C. Gutleb, A.C. Rijntjes, E. Murk, A.J. |
author_facet | Miller, I. Serchi, T. Cambier, S. Diepenbroek, C. Renaut, J. van den Berg, J.H.J. Kwadijk, C. Gutleb, A.C. Rijntjes, E. Murk, A.J. |
author_sort | Miller, I. |
collection | PubMed |
description | Female Wistar rats with different thyroid status (eu-, hypothyroid) were exposed to 0, 3 or 30 mg/kg body weight of the flame retardant HBCD for 7 days. Changes in protein patterns obtained by 2D-DIGE were evaluated, and different animal groups compared taking into account their exposure and thyroid status. Proteins significantly altered in abundance in any of these comparisons were identified by mass spectrometry. These data, together with hormone data of the animals, are discussed in “Hexa-bromocyclododecane (HBCD) induced changes in the liver proteome of eu- and hypothyroid female rats” (Miller et al., 2016) [1]. |
format | Online Article Text |
id | pubmed-4781926 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-47819262016-03-14 Dataset of liver proteins changed in eu- and hypothyroid female rats upon in vivo exposure to hexabromocyclododecane (HBCD) Miller, I. Serchi, T. Cambier, S. Diepenbroek, C. Renaut, J. van den Berg, J.H.J. Kwadijk, C. Gutleb, A.C. Rijntjes, E. Murk, A.J. Data Brief Data Article Female Wistar rats with different thyroid status (eu-, hypothyroid) were exposed to 0, 3 or 30 mg/kg body weight of the flame retardant HBCD for 7 days. Changes in protein patterns obtained by 2D-DIGE were evaluated, and different animal groups compared taking into account their exposure and thyroid status. Proteins significantly altered in abundance in any of these comparisons were identified by mass spectrometry. These data, together with hormone data of the animals, are discussed in “Hexa-bromocyclododecane (HBCD) induced changes in the liver proteome of eu- and hypothyroid female rats” (Miller et al., 2016) [1]. Elsevier 2016-02-27 /pmc/articles/PMC4781926/ /pubmed/26977443 http://dx.doi.org/10.1016/j.dib.2016.02.047 Text en © 2016 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Data Article Miller, I. Serchi, T. Cambier, S. Diepenbroek, C. Renaut, J. van den Berg, J.H.J. Kwadijk, C. Gutleb, A.C. Rijntjes, E. Murk, A.J. Dataset of liver proteins changed in eu- and hypothyroid female rats upon in vivo exposure to hexabromocyclododecane (HBCD) |
title | Dataset of liver proteins changed in eu- and hypothyroid female rats upon in vivo exposure to hexabromocyclododecane (HBCD) |
title_full | Dataset of liver proteins changed in eu- and hypothyroid female rats upon in vivo exposure to hexabromocyclododecane (HBCD) |
title_fullStr | Dataset of liver proteins changed in eu- and hypothyroid female rats upon in vivo exposure to hexabromocyclododecane (HBCD) |
title_full_unstemmed | Dataset of liver proteins changed in eu- and hypothyroid female rats upon in vivo exposure to hexabromocyclododecane (HBCD) |
title_short | Dataset of liver proteins changed in eu- and hypothyroid female rats upon in vivo exposure to hexabromocyclododecane (HBCD) |
title_sort | dataset of liver proteins changed in eu- and hypothyroid female rats upon in vivo exposure to hexabromocyclododecane (hbcd) |
topic | Data Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4781926/ https://www.ncbi.nlm.nih.gov/pubmed/26977443 http://dx.doi.org/10.1016/j.dib.2016.02.047 |
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