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Dataset of mouse hippocampus profiled by LC–MS/MS for label-free quantitation

This dataset reports on the analysis of mouse hippocampus by LC–MS/MS, from mice fed a diet that was either deficient in n-3 FA (n-3 Def) or sufficient in n-3 FA (n-3 Adq). Label free quantitative (LFQ) analysis of the mass spectrometry data identified 1008 quantifiable proteins, 115 of which were f...

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Detalles Bibliográficos
Autores principales: English, Jane A., Scaife, Caitriona, Harauma, Akiko, Focking, Melanie, Wynne, Kieran, Cagney, Gerard, Moriguchi, Toru, Cotter, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4781930/
https://www.ncbi.nlm.nih.gov/pubmed/26977433
http://dx.doi.org/10.1016/j.dib.2015.12.057
Descripción
Sumario:This dataset reports on the analysis of mouse hippocampus by LC–MS/MS, from mice fed a diet that was either deficient in n-3 FA (n-3 Def) or sufficient in n-3 FA (n-3 Adq). Label free quantitative (LFQ) analysis of the mass spectrometry data identified 1008 quantifiable proteins, 115 of which were found to be differentially expressed between the two dietary groups (n=8 per group). This data article refers to the research article “Omega-3 fatty acid deficiency disrupts endocytosis, neuritogenesis, and mitochondrial protein pathways in the mouse hippocampus” (English et al., 2013 [1]), in which a more comprehensive interpretation and analysis of the data is given.