Chimerism Analysis of Cell-Free DNA in Patients Treated with Hematopoietic Stem Cell Transplantation May Predict Early Relapse in Patients with Hematologic Malignancies

Background. We studied DNA chimerism in cell-free DNA (cfDNA) in patients treated with HSCT. Methods. Chimerism analysis was performed on CD3+ cells, polymorphonuclear (PMN) cells, and cfDNA using 16 small tandem repeat loci. The resulting labeled PCR-products were size-fractionated and quantified....

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Detalles Bibliográficos
Autores principales: Aljurf, Mahmoud, Abalkhail, Hala, Alseraihy, Amal, Mohamed, Said Y., Ayas, Mouhab, Alsharif, Fahad, Alzahrani, Hazza, Al-Jefri, Abdullah, Aldawsari, Ghuzayel, Al-Ahmari, Ali, Belgaumi, Asim F., Walter, Claudia Ulrike, El-Solh, Hassan, Rasheed, Walid, Albitar, Maher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4781938/
https://www.ncbi.nlm.nih.gov/pubmed/27006832
http://dx.doi.org/10.1155/2016/8589270

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