Cargando…

Data on individual metabolites of synthetic cannabinoids JWH-018, JWH-073 and AM2201 by Cunninghamella elegans

Synthetic cannabinoids JWH-018, JWH-073 and AM2201 were metabolised by the fungus Cunninghamella elegans. In this article, data on individual metabolites of their retention times, mass accuracies, major product ions and structures indicated by product ions are presented. The data in this article is...

Descripción completa

Detalles Bibliográficos
Autores principales:	Watanabe, Shimpei, Kuzhiumparambil, Unnikrishnan, Winiarski, Zophia, Fu, Shanlin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Data Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4781962/ https://www.ncbi.nlm.nih.gov/pubmed/26977432 http://dx.doi.org/10.1016/j.dib.2016.02.039

Ejemplares similares

Dependence Potential of the Synthetic Cannabinoids JWH-073, JWH-081, and JWH-210: In Vivo and In Vitro Approaches
por: Cha, Hye Jin, et al.
Publicado: (2014)

Neurotoxicity of Synthetic Cannabinoids JWH-081 and JWH-210
por: Cha, Hye Jin, et al.
Publicado: (2015)

In vitro metabolism of synthetic cannabinoid AM1220 by human liver microsomes and Cunninghamella elegans using liquid chromatography coupled with high resolution mass spectrometry
por: Watanabe, Shimpei, et al.
Publicado: (2018)

Assessment of the Abuse Liability of Synthetic Cannabinoid Agonists JWH-030, JWH-175, and JWH-176
por: Tampus, Reinholdgher, et al.
Publicado: (2015)

Behavioral and Pharmacokinetic Profile of Indole-Derived Synthetic Cannabinoids JWH-073 and JWH-210 as Compared to the Phytocannabinoid Δ(9)-THC in Rats
por: Uttl, Libor, et al.
Publicado: (2018)

Self-Administration of JWH-018 A Synthetic Cannabinoid in Experimentally Naïve Rats
por: Hiranita, Takato
Publicado: (2015)

Elevation of endocannabinoids in the brain by synthetic cannabinoid JWH-018: mechanism and effect on learning and memory
por: Li, Ren-shi, et al.
Publicado: (2019)

In Vivo Bio-Activation of JWH-175 to JWH-018: Pharmacodynamic and Pharmacokinetic Studies in Mice
por: Tirri, Micaela, et al.
Publicado: (2022)

Synthetic cannabinoid JWH-073 alters both acute behavior and in vivo/vitro electrophysiological responses in mice
por: Barbieri, Mario, et al.
Publicado: (2022)

Neurocognition and Subjective Experience Following Acute Doses of the Synthetic Cannabinoid JWH-018: Responders Versus Nonresponders
por: Theunissen, Eef L., et al.
Publicado: (2019)

Psychotomimetic symptoms after a moderate dose of a synthetic cannabinoid (JWH-018): implications for psychosis
por: Theunissen, Eef L., et al.
Publicado: (2021)

Natural (∆(9)-THC) and synthetic (JWH-018) cannabinoids induce seizures by acting through the cannabinoid CB(1) receptor
por: Malyshevskaya, Olga, et al.
Publicado: (2017)

Phase I Hydroxylated Metabolites of the K2 Synthetic Cannabinoid JWH-018 Retain In Vitro and In Vivo Cannabinoid 1 Receptor Affinity and Activity
por: Brents, Lisa K., et al.
Publicado: (2011)

Psychostimulant Effect of the Synthetic Cannabinoid JWH-018 and AKB48: Behavioral, Neurochemical, and Dopamine Transporter Scan Imaging Studies in Mice
por: Ossato, Andrea, et al.
Publicado: (2017)

Adolescent self-administration of the synthetic cannabinoid receptor agonist JWH-018 induces neurobiological and behavioral alterations in adult male mice
por: Margiani, Giulia, et al.
Publicado: (2022)

Acute Pharmacological Effects and Oral Fluid Concentrations of the Synthetic Cannabinoids JWH-122 and JWH-210 in Humans After Self-Administration: An Observational Study
por: Martínez, Lucia, et al.
Publicado: (2021)

Correction to: Adolescent self‑administration of the synthetic cannabinoid receptor agonist JWH‑018 induces neurobiological and behavioral alterations in adult male mice
por: Margiani, Giulia, et al.
Publicado: (2023)

Determination of the Synthetic Cannabinoids JWH-122, JWH-210, UR-144 in Oral Fluid of Consumers by GC-MS and Quantification of Parent Compounds and Metabolites by UHPLC-MS/MS
por: La Maida, Nunzia, et al.
Publicado: (2020)

Repeated Exposure to the “Spice” Cannabinoid JWH-018 Induces Tolerance and Enhances Responsiveness to 5-HT(1A) Receptor Stimulation in Male Rats
por: Elmore, Joshua S., et al.
Publicado: (2018)

Deletion of Cryab increases the vulnerability of mice to the addiction-like effects of the cannabinoid JWH-018 via upregulation of striatal NF-κB expression
por: Sayson, Leandro Val, et al.
Publicado: (2023)

Distribution of Synthetic Cannabinoids JWH-210, RCS-4 and ∆ 9-Tetrahydrocannabinol After Intravenous Administration to Pigs
por: Schaefer, Nadine, et al.
Publicado: (2017)

Adolescent exposure to the Spice/K2 cannabinoid JWH-018 impairs sensorimotor gating and alters cortical perineuronal nets in a sex-dependent manner
por: Izquierdo-Luengo, Cristina, et al.
Publicado: (2023)

Behavioral Effects of Developmental Exposure to JWH-018 in Wild-Type and Disrupted in Schizophrenia 1 (disc1) Mutant Zebrafish
por: García-González, Judit, et al.
Publicado: (2021)

Acute Cardiovascular and Cardiorespiratory Effects of JWH-018 in Awake and Freely Moving Mice: Mechanism of Action and Possible Antidotal Interventions?
por: Marchetti, Beatrice, et al.
Publicado: (2023)

Repeated exposure to JWH‐018 induces adaptive changes in the mesolimbic and mesocortical dopaminergic pathways, glial cells alterations, and behavioural correlates
por: Pintori, Nicholas, et al.
Publicado: (2021)

PM291. Synthetic cannabinoid JWH-210 induces motor impairments through the regulation of neurotransmission in tetanus toxin-treated mice
por: Yun, Jaesuk, et al.
Publicado: (2016)

Activation of cannabinoid receptor type 2 by JWH133 alleviates bleomycin-induced pulmonary fibrosis in mice
por: Fu, Qiang, et al.
Publicado: (2017)

The Old and the New: Cardiovascular and Respiratory Alterations Induced by Acute JWH-018 Administration Compared to Δ(9)-THC—A Preclinical Study in Mice
por: Marchetti, Beatrice, et al.
Publicado: (2023)

Modulation of breast cancer cell viability by a cannabinoid receptor 2 agonist, JWH-015, is calcium dependent
por: Hanlon, Katherine E, et al.
Publicado: (2016)

Lateral flow immunoassay and enzyme linked immunosorbent assay as effective immunomethods for the detection of synthetic cannabinoid JWH-200 based on the newly synthesized hapten
por: Fojtíková, Lucie, et al.
Publicado: (2017)

Cytotoxicity, metabolism, and isozyme mapping of the synthetic cannabinoids JWH-200, A-796260, and 5F-EMB-PINACA studied by means of in vitro systems
por: Gampfer, Tanja M., et al.
Publicado: (2021)

Time- and temperature-dependent postmortem concentration changes of the (synthetic) cannabinoids JWH-210, RCS-4, as well as ∆9-tetrahydrocannabinol following pulmonary administration to pigs
por: Schaefer, Nadine, et al.
Publicado: (2020)

Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)-Methanandamide and JWH-015: Involvement of CB(2)
por: Olea-Herrero, N, et al.
Publicado: (2009)

Cannabinoid receptor type 2 agonist JWH-133 decreases cathepsin B secretion and neurotoxicity from HIV-infected macrophages
por: Rosario-Rodríguez, Lester J., et al.
Publicado: (2022)

Strategies to distinguish new synthetic cannabinoid FUBIMINA (BIM-2201) intake from its isomer THJ-2201: metabolism of FUBIMINA in human hepatocytes
por: Diao, Xingxing, et al.
Publicado: (2016)

Is adipose tissue suitable for detection of (synthetic) cannabinoids? A comparative study analyzing antemortem and postmortem specimens following pulmonary administration of JWH-210, RCS-4, as well as ∆9-tetrahydrocannabinol to pigs
por: Schaefer, Nadine, et al.
Publicado: (2020)

Anti-Obesity Effect of the CB2 Receptor Agonist JWH-015 in Diet-Induced Obese Mice
por: Verty, A. N. A., et al.
Publicado: (2015)

Modified Alginate-Based Hydrogel as a Carrier of the CB2 Agonist JWH133 for Bone Engineering
por: Zhou, Wei, et al.
Publicado: (2021)

Isolation and Characterization of Three Unrecorded Zygomycete Fungi in Korea: Cunninghamella bertholletiae, Cunninghamella echinulata, and Cunninghamella elegans
por: Nguyen, Thuong T. T., et al.
Publicado: (2017)

Cannabinoid receptor 2-selective agonist JWH015 attenuates bone cancer pain through the amelioration of impaired autophagy flux induced by inflammatory mediators in the spinal cord
por: Mao, Yanting, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ir83mmnss6ebgds8s92hlg0ifc