Validation, optimisation, and application data in support of the development of a targeted selected ion monitoring assay for degraded cardiac troponin T

Cardiac troponin T (cTnT) fragmentation in human serum was investigated using a newly developed targeted selected ion monitoring assay, as described in the accompanying article: “Development of a targeted selected ion monitoring assay for the elucidation of protease induced structural changes in car...

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Autores principales: Streng, Alexander S., de Boer, Douwe, Bouwman, Freek G., Mariman, Edwin C.M., Scholten, Arjen, van Dieijen-Visser, Marja P., Wodzig, Will K.W.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Data Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782000/
https://www.ncbi.nlm.nih.gov/pubmed/26977445
http://dx.doi.org/10.1016/j.dib.2016.02.051
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author Streng, Alexander S.
de Boer, Douwe
Bouwman, Freek G.
Mariman, Edwin C.M.
Scholten, Arjen
van Dieijen-Visser, Marja P.
Wodzig, Will K.W.H.
author_facet Streng, Alexander S.
de Boer, Douwe
Bouwman, Freek G.
Mariman, Edwin C.M.
Scholten, Arjen
van Dieijen-Visser, Marja P.
Wodzig, Will K.W.H.
author_sort Streng, Alexander S.
collection PubMed
description Cardiac troponin T (cTnT) fragmentation in human serum was investigated using a newly developed targeted selected ion monitoring assay, as described in the accompanying article: “Development of a targeted selected ion monitoring assay for the elucidation of protease induced structural changes in cardiac troponin T” [1]. This article presents data describing aspects of the validation and optimisation of this assay. The data consists of several figures, an excel file containing the results of a sequence identity search, and a description of the raw mass spectrometry (MS) data files, deposited in the ProteomeXchange repository with id PRIDE: PXD003187.
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spelling pubmed-47820002016-03-14 Validation, optimisation, and application data in support of the development of a targeted selected ion monitoring assay for degraded cardiac troponin T Streng, Alexander S. de Boer, Douwe Bouwman, Freek G. Mariman, Edwin C.M. Scholten, Arjen van Dieijen-Visser, Marja P. Wodzig, Will K.W.H. Data Brief Data Article Cardiac troponin T (cTnT) fragmentation in human serum was investigated using a newly developed targeted selected ion monitoring assay, as described in the accompanying article: “Development of a targeted selected ion monitoring assay for the elucidation of protease induced structural changes in cardiac troponin T” [1]. This article presents data describing aspects of the validation and optimisation of this assay. The data consists of several figures, an excel file containing the results of a sequence identity search, and a description of the raw mass spectrometry (MS) data files, deposited in the ProteomeXchange repository with id PRIDE: PXD003187. Elsevier 2016-03-03 /pmc/articles/PMC4782000/ /pubmed/26977445 http://dx.doi.org/10.1016/j.dib.2016.02.051 Text en © 2016 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Data Article
Streng, Alexander S.
de Boer, Douwe
Bouwman, Freek G.
Mariman, Edwin C.M.
Scholten, Arjen
van Dieijen-Visser, Marja P.
Wodzig, Will K.W.H.
Validation, optimisation, and application data in support of the development of a targeted selected ion monitoring assay for degraded cardiac troponin T
title Validation, optimisation, and application data in support of the development of a targeted selected ion monitoring assay for degraded cardiac troponin T
title_full Validation, optimisation, and application data in support of the development of a targeted selected ion monitoring assay for degraded cardiac troponin T
title_fullStr Validation, optimisation, and application data in support of the development of a targeted selected ion monitoring assay for degraded cardiac troponin T
title_full_unstemmed Validation, optimisation, and application data in support of the development of a targeted selected ion monitoring assay for degraded cardiac troponin T
title_short Validation, optimisation, and application data in support of the development of a targeted selected ion monitoring assay for degraded cardiac troponin T
title_sort validation, optimisation, and application data in support of the development of a targeted selected ion monitoring assay for degraded cardiac troponin t
topic Data Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782000/
https://www.ncbi.nlm.nih.gov/pubmed/26977445
http://dx.doi.org/10.1016/j.dib.2016.02.051
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