Hypoxia promotes drug resistance in osteosarcoma cells via activating AMP-activated protein kinase (AMPK) signaling

PURPOSE: Drug resistance has been recognized to be a major obstacle to the chemotherapy for osteosarcoma. And the potential importance of hypoxia as a target to reverse drug resistance in osteosarcoma has been indicated, though the mechanism underlining such role is not clarified. The present study...

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Detalles Bibliográficos
Autores principales: Zhao, Changfu, Zhang, Qiao, Yu, Tao, Sun, Shudong, Wang, Wenjun, Liu, Guangyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782021/
https://www.ncbi.nlm.nih.gov/pubmed/26998423
http://dx.doi.org/10.1016/j.jbo.2016.01.002

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