Statistical Enrichment of Epigenetic States Around Triplet Repeats that Can Undergo Expansions

More than 30 human genetic diseases are linked to tri-nucleotide repeat expansions. There is no known mechanism that explains repeat expansions in full, but changes in the epigenetic state of the associated locus has been implicated in the disease pathology for a growing number of examples. A compre...

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Detalles Bibliográficos
Autores principales: Essebier, Alexandra, Vera Wolf, Patricia, Cao, Minh Duc, Carroll, Bernard J., Balasubramanian, Sureshkumar, Bodén, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782033/
https://www.ncbi.nlm.nih.gov/pubmed/27013954
http://dx.doi.org/10.3389/fnins.2016.00092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782033/
https://www.ncbi.nlm.nih.gov/pubmed/27013954
http://dx.doi.org/10.3389/fnins.2016.00092

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