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Statistical Enrichment of Epigenetic States Around Triplet Repeats that Can Undergo Expansions
More than 30 human genetic diseases are linked to tri-nucleotide repeat expansions. There is no known mechanism that explains repeat expansions in full, but changes in the epigenetic state of the associated locus has been implicated in the disease pathology for a growing number of examples. A compre...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782033/ https://www.ncbi.nlm.nih.gov/pubmed/27013954 http://dx.doi.org/10.3389/fnins.2016.00092 |