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Facilitating Mitochondrial Calcium Uptake Improves Activation-Induced Cerebral Blood Flow and Behavior after mTBI

Mild to moderate traumatic brain injury (mTBI) leads to secondary neuronal loss via excitotoxic mechanisms, including mitochondrial Ca(2+) overload. However, in the surviving cellular population, mitochondrial Ca(2+) influx, and oxidative metabolism are diminished leading to suboptimal neuronal circ...

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Detalles Bibliográficos
Autores principales: Murugan, Madhuvika, Santhakumar, Vijayalakshmi, Kannurpatti, Sridhar S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782040/
https://www.ncbi.nlm.nih.gov/pubmed/27013987
http://dx.doi.org/10.3389/fnsys.2016.00019

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