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SR proteins are NXF1 adaptors that link alternative RNA processing to mRNA export

Nuclear export factor 1 (NXF1) exports mRNA to the cytoplasm after recruitment to mRNA by specific adaptor proteins. How and why cells use numerous different export adaptors is poorly understood. Here we critically evaluate members of the SR protein family (SRSF1–7) for their potential to act as NXF...

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Detalles Bibliográficos
Autores principales: Müller-McNicoll, Michaela, Botti, Valentina, de Jesus Domingues, Antonio M., Brandl, Holger, Schwich, Oliver D., Steiner, Michaela C., Curk, Tomaz, Poser, Ina, Zarnack, Kathi, Neugebauer, Karla M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782049/
https://www.ncbi.nlm.nih.gov/pubmed/26944680
http://dx.doi.org/10.1101/gad.276477.115