Generation of Fibroblasts Lacking the Sal-like 1 Gene by Using Transcription Activator-like Effector Nuclease-mediated Homologous Recombination

The Sal-like 1 gene (Sall1) is essential for kidney development, and mutations in this gene result in abnormalities in the kidneys. Mice lacking Sall1 show agenesis or severe dysgenesis of the kidneys. In a recent study, blastocyst complementation was used to develop mice and pigs with exogenic orga...

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Detalles Bibliográficos
Autores principales: Kim, Se Eun, Kim, Ji Woo, Kim, Yeong Ji, Kwon, Deug-Nam, Kim, Jin-Hoi, Kang, Man-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian-Australasian Association of Animal Production Societies (AAAP) and Korean Society of Animal Science and Technology (KSAST) 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782092/
https://www.ncbi.nlm.nih.gov/pubmed/26949958
http://dx.doi.org/10.5713/ajas.15.0244

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