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Mismatch repair status in patients with primary operable colorectal cancer: associations with the local and systemic tumour environment
BACKGROUND: Mismatch repair-deficient (dMMR) colorectal cancer (CRC) is associated with a conspicuous local immune infiltrate; however, its relationship with systemic inflammatory responses remains to be determined. The present study aims to examine the relationships and prognostic value of assessme...
Autores principales: | Park, James H, Powell, Arfon G, Roxburgh, Campbell S D, Horgan, Paul G, McMillan, Donald C, Edwards, Joanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782207/ https://www.ncbi.nlm.nih.gov/pubmed/26859693 http://dx.doi.org/10.1038/bjc.2016.17 |
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