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Efficient derivation of dopaminergic neurons from SOX1(−) floor plate cells under defined culture conditions

BACKGROUND: Parkinson’s disease (PD) is a severe neurodegenerative disease associated with loss of dopaminergic neurons. Derivation of dopaminergic neurons from human embryonic stem cells (hESCs) could provide new therapeutic options for PD therapy. Dopaminergic neurons are derived from SOX(−) floor...

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Detalles Bibliográficos
Autores principales:	Li, Mingming, Zou, Yu, Lu, Qiqi, Tang, Ning, Heng, Alexis, Islam, Intekhab, Tong, Huei Jinn, Dawe, Gavin S., Cao, Tong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782356/ https://www.ncbi.nlm.nih.gov/pubmed/26956435 http://dx.doi.org/10.1186/s12929-016-0251-6

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