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Lack of cortistatin or somatostatin differentially influences DMBA-induced mammary gland tumorigenesis in mice in an obesity-dependent mode

BACKGROUND: Somatostatin (SST) and cortistatin (CORT), two structurally and functionally related peptides, share a family of widespread receptors (sst1-5) to exert apparently similar biological actions, including endocrine/metabolic regulation and suppression of tumor cell proliferation. However, de...

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Detalles Bibliográficos
Autores principales: Luque, Raúl M., Villa-Osaba, Alicia, L-López, Fernando, Pozo-Salas, Ana I., Sánchez-Sánchez, Rafael, Ortega-Salas, Rosa, de Lecea, Luis, Álvarez-Benito, Marina, López-Miranda, José, Gahete, Manuel D., Castaño, Justo P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782371/
https://www.ncbi.nlm.nih.gov/pubmed/26956474
http://dx.doi.org/10.1186/s13058-016-0689-1

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