Wnt3a upregulates brain-derived insulin by increasing NeuroD1 via Wnt/β-catenin signaling in the hypothalamus

BACKGROUND: Insulin plays diverse roles in the brain. Although insulin produced by pancreatic β-cells that crosses the blood–brain barrier is a major source of brain insulin, recent studies suggest that insulin is also produced locally within the brain. However, the mechanisms underlying the product...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Jaemeun, Kim, Kyungchan, Yu, Seong-Woon, Kim, Eun-Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782570/
https://www.ncbi.nlm.nih.gov/pubmed/26956881
http://dx.doi.org/10.1186/s13041-016-0207-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782570/
https://www.ncbi.nlm.nih.gov/pubmed/26956881
http://dx.doi.org/10.1186/s13041-016-0207-5

Ejemplares similares