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Tissue-independent and tissue-specific patterns of DNA methylation alteration in cancer
BACKGROUND: There is growing evidence that DNA methylation alterations contribute to carcinogenesis. While cancer tissue exhibits widespread DNA methylation changes, the proportion of tissue-specific versus tissue-independent DNA methylation alterations in cancer is unclear. In addition, it is unkno...
Autores principales: | Chen, Yuting, Breeze, Charles E., Zhen, Shao, Beck, Stephan, Teschendorff, Andrew E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782576/ https://www.ncbi.nlm.nih.gov/pubmed/26958079 http://dx.doi.org/10.1186/s13072-016-0058-4 |
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