Use of clobetasol in lacquer for plaque psoriasis treatment

Clobetasol benefits to control psoriasis lesions are well defined, but there were not studies about its action when used in lacquer vehicle to control skin lesions. A double-blind study was conducted with 40 patients that utilized clobetasol 0.05% in one hemibody and just the vehicle in the other he...

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Detalles Bibliográficos
Autores principales: da Silva, Suze Aparecida, Magalhães, Renata Ferreira, Torres, Rafael Augusto Tamasauskas, de Oliveira, Raquel Diana, Velho, Paulo Eduardo Neves Ferreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2016
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782662/
https://www.ncbi.nlm.nih.gov/pubmed/26982794
http://dx.doi.org/10.1590/abd1806-4841.20164228
Descripción
Sumario:Clobetasol benefits to control psoriasis lesions are well defined, but there were not studies about its action when used in lacquer vehicle to control skin lesions. A double-blind study was conducted with 40 patients that utilized clobetasol 0.05% in one hemibody and just the vehicle in the other hemibody. Twenty of them used petrolatum as vehicle and the others used lacquer. An assessment was conducted using the clinical index PASI and a quality of life questionnaire (Dermatological Life Quality Index). There was no statistical difference between groups. There was a trend of favorable response particularly in the hemibody treated with clobetasol.

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