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Use of clobetasol in lacquer for plaque psoriasis treatment
Clobetasol benefits to control psoriasis lesions are well defined, but there were not studies about its action when used in lacquer vehicle to control skin lesions. A double-blind study was conducted with 40 patients that utilized clobetasol 0.05% in one hemibody and just the vehicle in the other he...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Dermatologia
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782662/ https://www.ncbi.nlm.nih.gov/pubmed/26982794 http://dx.doi.org/10.1590/abd1806-4841.20164228 |
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author | da Silva, Suze Aparecida Magalhães, Renata Ferreira Torres, Rafael Augusto Tamasauskas de Oliveira, Raquel Diana Velho, Paulo Eduardo Neves Ferreira |
author_facet | da Silva, Suze Aparecida Magalhães, Renata Ferreira Torres, Rafael Augusto Tamasauskas de Oliveira, Raquel Diana Velho, Paulo Eduardo Neves Ferreira |
author_sort | da Silva, Suze Aparecida |
collection | PubMed |
description | Clobetasol benefits to control psoriasis lesions are well defined, but there were not studies about its action when used in lacquer vehicle to control skin lesions. A double-blind study was conducted with 40 patients that utilized clobetasol 0.05% in one hemibody and just the vehicle in the other hemibody. Twenty of them used petrolatum as vehicle and the others used lacquer. An assessment was conducted using the clinical index PASI and a quality of life questionnaire (Dermatological Life Quality Index). There was no statistical difference between groups. There was a trend of favorable response particularly in the hemibody treated with clobetasol. |
format | Online Article Text |
id | pubmed-4782662 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Sociedade Brasileira de Dermatologia |
record_format | MEDLINE/PubMed |
spelling | pubmed-47826622016-03-10 Use of clobetasol in lacquer for plaque psoriasis treatment da Silva, Suze Aparecida Magalhães, Renata Ferreira Torres, Rafael Augusto Tamasauskas de Oliveira, Raquel Diana Velho, Paulo Eduardo Neves Ferreira An Bras Dermatol Communication Clobetasol benefits to control psoriasis lesions are well defined, but there were not studies about its action when used in lacquer vehicle to control skin lesions. A double-blind study was conducted with 40 patients that utilized clobetasol 0.05% in one hemibody and just the vehicle in the other hemibody. Twenty of them used petrolatum as vehicle and the others used lacquer. An assessment was conducted using the clinical index PASI and a quality of life questionnaire (Dermatological Life Quality Index). There was no statistical difference between groups. There was a trend of favorable response particularly in the hemibody treated with clobetasol. Sociedade Brasileira de Dermatologia 2016 /pmc/articles/PMC4782662/ /pubmed/26982794 http://dx.doi.org/10.1590/abd1806-4841.20164228 Text en © 2016 by Anais Brasileiros de Dermatologia http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the original work is properly cited. |
spellingShingle | Communication da Silva, Suze Aparecida Magalhães, Renata Ferreira Torres, Rafael Augusto Tamasauskas de Oliveira, Raquel Diana Velho, Paulo Eduardo Neves Ferreira Use of clobetasol in lacquer for plaque psoriasis treatment |
title | Use of clobetasol in lacquer for plaque psoriasis treatment |
title_full | Use of clobetasol in lacquer for plaque psoriasis treatment |
title_fullStr | Use of clobetasol in lacquer for plaque psoriasis treatment |
title_full_unstemmed | Use of clobetasol in lacquer for plaque psoriasis treatment |
title_short | Use of clobetasol in lacquer for plaque psoriasis treatment |
title_sort | use of clobetasol in lacquer for plaque psoriasis treatment |
topic | Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782662/ https://www.ncbi.nlm.nih.gov/pubmed/26982794 http://dx.doi.org/10.1590/abd1806-4841.20164228 |
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