Autophagy Induction Protects Against 7-Oxysterol-induced Cell Death via Lysosomal Pathway and Oxidative Stress

7-Oxysterols are major toxic components in oxidized low-density lipoprotein and human atheroma lesions, which cause lysosomal membrane permeabilization (LMP) and cell death. Autophagy may function as a survival mechanism in this process. Here, we investigated whether 7-oxysterols mixed in an atherom...

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Detalles Bibliográficos
Autores principales: Yuan, Xi-Ming, Sultana, Nargis, Siraj, Nabeel, Ward, Liam J., Ghafouri, Bijar, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782829/
https://www.ncbi.nlm.nih.gov/pubmed/26966389
http://dx.doi.org/10.4137/JCD.S37841

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