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Acupuncture and Related Therapies for Symptom Management in Palliative Cancer Care: Systematic Review and Meta-Analysis

Available systematic reviews showed uncertainty on the effectiveness of using acupuncture and related therapies for palliative cancer care. The aim of this systematic review and meta-analysis was to summarize current best evidence on acupuncture and related therapies for palliative cancer care. Five...

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Autores principales: Lau, Charlotte H. Y., Wu, Xinyin, Chung, Vincent C. H., Liu, Xin, Hui, Edwin P., Cramer, Holger, Lauche, Romy, Wong, Samuel Y. S., Lau, Alexander Y. L., Sit, Regina S. T., Ziea, Eric T. C., Ng, Bacon F. L., Wu, Justin C. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782866/
https://www.ncbi.nlm.nih.gov/pubmed/26945382
http://dx.doi.org/10.1097/MD.0000000000002901
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author Lau, Charlotte H. Y.
Wu, Xinyin
Chung, Vincent C. H.
Liu, Xin
Hui, Edwin P.
Cramer, Holger
Lauche, Romy
Wong, Samuel Y. S.
Lau, Alexander Y. L.
Sit, Regina S. T.
Ziea, Eric T. C.
Ng, Bacon F. L.
Wu, Justin C. Y.
author_facet Lau, Charlotte H. Y.
Wu, Xinyin
Chung, Vincent C. H.
Liu, Xin
Hui, Edwin P.
Cramer, Holger
Lauche, Romy
Wong, Samuel Y. S.
Lau, Alexander Y. L.
Sit, Regina S. T.
Ziea, Eric T. C.
Ng, Bacon F. L.
Wu, Justin C. Y.
author_sort Lau, Charlotte H. Y.
collection PubMed
description Available systematic reviews showed uncertainty on the effectiveness of using acupuncture and related therapies for palliative cancer care. The aim of this systematic review and meta-analysis was to summarize current best evidence on acupuncture and related therapies for palliative cancer care. Five international and 3 Chinese databases were searched. Randomized controlled trials (RCTs) comparing acupuncture and related therapies with conventional or sham treatments were considered. Primary outcomes included fatigue, paresthesia and dysesthesias, chronic pain, anorexia, insomnia, limb edema, constipation, and health-related quality of life, of which effective conventional interventions are limited. Thirteen RCTs were included. Compared with conventional interventions, meta-analysis demonstrated that acupuncture and related therapies significantly reduced pain (2 studies, n = 175, pooled weighted mean difference: −0.76, 95% confidence interval: −0.14 to −0.39) among patients with liver or gastric cancer. Combined use of acupuncture and related therapies and Chinese herbal medicine improved quality of life in patients with gastrointestinal cancer (2 studies, n = 111, pooled standard mean difference: 0.75, 95% confidence interval: 0.36–1.13). Acupressure showed significant efficacy in reducing fatigue in lung cancer patients when compared with sham acupressure. Adverse events for acupuncture and related therapies were infrequent and mild. Acupuncture and related therapies are effective in reducing pain, fatigue, and in improving quality of life when compared with conventional intervention alone among cancer patients. Limitations on current evidence body imply that they should be used as a complement, rather than an alternative, to conventional care. Effectiveness of acupuncture and related therapies for managing anorexia, reducing constipation, paresthesia and dysesthesia, insomnia, and limb edema in cancer patients is uncertain, warranting future RCTs in these areas.
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spelling pubmed-47828662016-03-24 Acupuncture and Related Therapies for Symptom Management in Palliative Cancer Care: Systematic Review and Meta-Analysis Lau, Charlotte H. Y. Wu, Xinyin Chung, Vincent C. H. Liu, Xin Hui, Edwin P. Cramer, Holger Lauche, Romy Wong, Samuel Y. S. Lau, Alexander Y. L. Sit, Regina S. T. Ziea, Eric T. C. Ng, Bacon F. L. Wu, Justin C. Y. Medicine (Baltimore) 3800 Available systematic reviews showed uncertainty on the effectiveness of using acupuncture and related therapies for palliative cancer care. The aim of this systematic review and meta-analysis was to summarize current best evidence on acupuncture and related therapies for palliative cancer care. Five international and 3 Chinese databases were searched. Randomized controlled trials (RCTs) comparing acupuncture and related therapies with conventional or sham treatments were considered. Primary outcomes included fatigue, paresthesia and dysesthesias, chronic pain, anorexia, insomnia, limb edema, constipation, and health-related quality of life, of which effective conventional interventions are limited. Thirteen RCTs were included. Compared with conventional interventions, meta-analysis demonstrated that acupuncture and related therapies significantly reduced pain (2 studies, n = 175, pooled weighted mean difference: −0.76, 95% confidence interval: −0.14 to −0.39) among patients with liver or gastric cancer. Combined use of acupuncture and related therapies and Chinese herbal medicine improved quality of life in patients with gastrointestinal cancer (2 studies, n = 111, pooled standard mean difference: 0.75, 95% confidence interval: 0.36–1.13). Acupressure showed significant efficacy in reducing fatigue in lung cancer patients when compared with sham acupressure. Adverse events for acupuncture and related therapies were infrequent and mild. Acupuncture and related therapies are effective in reducing pain, fatigue, and in improving quality of life when compared with conventional intervention alone among cancer patients. Limitations on current evidence body imply that they should be used as a complement, rather than an alternative, to conventional care. Effectiveness of acupuncture and related therapies for managing anorexia, reducing constipation, paresthesia and dysesthesia, insomnia, and limb edema in cancer patients is uncertain, warranting future RCTs in these areas. Wolters Kluwer Health 2016-03-07 /pmc/articles/PMC4782866/ /pubmed/26945382 http://dx.doi.org/10.1097/MD.0000000000002901 Text en Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0, where it is permissible to download, share and reproduce the work in any medium, provided it is properly cited. The work cannot be changed in any way or used commercially. http://creativecommons.org/licenses/by-nc-nd/4.0
spellingShingle 3800
Lau, Charlotte H. Y.
Wu, Xinyin
Chung, Vincent C. H.
Liu, Xin
Hui, Edwin P.
Cramer, Holger
Lauche, Romy
Wong, Samuel Y. S.
Lau, Alexander Y. L.
Sit, Regina S. T.
Ziea, Eric T. C.
Ng, Bacon F. L.
Wu, Justin C. Y.
Acupuncture and Related Therapies for Symptom Management in Palliative Cancer Care: Systematic Review and Meta-Analysis
title Acupuncture and Related Therapies for Symptom Management in Palliative Cancer Care: Systematic Review and Meta-Analysis
title_full Acupuncture and Related Therapies for Symptom Management in Palliative Cancer Care: Systematic Review and Meta-Analysis
title_fullStr Acupuncture and Related Therapies for Symptom Management in Palliative Cancer Care: Systematic Review and Meta-Analysis
title_full_unstemmed Acupuncture and Related Therapies for Symptom Management in Palliative Cancer Care: Systematic Review and Meta-Analysis
title_short Acupuncture and Related Therapies for Symptom Management in Palliative Cancer Care: Systematic Review and Meta-Analysis
title_sort acupuncture and related therapies for symptom management in palliative cancer care: systematic review and meta-analysis
topic 3800
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782866/
https://www.ncbi.nlm.nih.gov/pubmed/26945382
http://dx.doi.org/10.1097/MD.0000000000002901
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