Combinatorial treatment with oncolytic adenovirus and helper-dependent adenovirus augments adenoviral cancer gene therapy

Oncolytic adenoviruses (Onc.Ads) produce significant antitumor effects but as single agents they rarely eliminate tumors. Investigators have therefore incorporated sequences into these vectors that encode immunomodulatory molecules to enhance antitumor immunity. Successful implementation of this str...

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Detalles Bibliográficos
Autores principales: Farzad, Lisa, Cerullo, Vincenzo, Yagyu, Shigeki, Bertin, Terry, Hemminki, Akseli, Rooney, Cliona, Lee, Brendan, Suzuki, Masataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782941/
https://www.ncbi.nlm.nih.gov/pubmed/27119096
http://dx.doi.org/10.1038/mto.2014.8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782941/
https://www.ncbi.nlm.nih.gov/pubmed/27119096
http://dx.doi.org/10.1038/mto.2014.8

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