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Antimelanoma CTL recognizes peptides derived from an ORF transcribed from the antisense strand of the 3′ untranslated region of TRIT1

Noncoding regions of the genome play an important role in tumorigenesis of cancer. Using expression cloning, we have identified a cytotoxic T lymphocyte (CTL)–defined antigen that recognizes a protein sequence derived from an open reading frame transcribed from the reverse strand in the 3′ untransla...

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Detalles Bibliográficos
Autores principales: Swoboda, Rolf K, Somasundaram, Rajasekharan, Caputo-Gross, Laura, Marincola, Francesco M, Robbins, Paul, Herlyn, Meenhard, Herlyn, Dorothee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782943/
https://www.ncbi.nlm.nih.gov/pubmed/27119099
http://dx.doi.org/10.1038/mto.2014.9