Intratumoral INF-γ triggers an antiviral state in GL261 tumor cells: a major hurdle to overcome for oncolytic vaccinia virus therapy of cancer

Oncolytic vaccinia virus (VACV) therapy is an alternative treatment option for glioblastoma multiforme. Here, we used a comparison of different tumor locations and different immunologic and genetic backgrounds to determine the replication efficacy and oncolytic potential of the VACV LIVP 1.1.1, an a...

Descripción completa

Detalles Bibliográficos
Autores principales: Kober, Christina, Weibel, Stephanie, Rohn, Susanne, Kirscher, Lorenz, Szalay, Aladar A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782962/
https://www.ncbi.nlm.nih.gov/pubmed/27119106
http://dx.doi.org/10.1038/mto.2015.9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782962/
https://www.ncbi.nlm.nih.gov/pubmed/27119106
http://dx.doi.org/10.1038/mto.2015.9

Ejemplares similares