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A Human "eFP" Browser for Generating Gene Expression Anatograms
Transcriptomic studies help to further our understanding of gene function. Human transcriptomic studies tend to focus on a particular subset of tissue types or a particular disease state; however, it is possible to collate into a compendium multiple studies that have been profiled using the same exp...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783024/ https://www.ncbi.nlm.nih.gov/pubmed/26954504 http://dx.doi.org/10.1371/journal.pone.0150982 |
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author | Patel, Rohan V. Hamanishi, Erin T. Provart, Nicholas J. |
author_facet | Patel, Rohan V. Hamanishi, Erin T. Provart, Nicholas J. |
author_sort | Patel, Rohan V. |
collection | PubMed |
description | Transcriptomic studies help to further our understanding of gene function. Human transcriptomic studies tend to focus on a particular subset of tissue types or a particular disease state; however, it is possible to collate into a compendium multiple studies that have been profiled using the same expression analysis platform to provide an overview of gene expression levels in many different tissues or under different conditions. In order to increase the knowledge and understanding we gain from such studies, intuitive visualization of gene expression data in such a compendium can be useful. The Human eFP (“electronic Fluorescent Pictograph”) Browser presented here is a tool for intuitive visualization of large human gene expression data sets on pictographic representations of the human body as gene expression “anatograms”. Pictographic representations for new data sets may be generated easily. The Human eFP Browser can also serve as a portal to other gene-specific information through link-outs to various online resources. |
format | Online Article Text |
id | pubmed-4783024 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-47830242016-03-23 A Human "eFP" Browser for Generating Gene Expression Anatograms Patel, Rohan V. Hamanishi, Erin T. Provart, Nicholas J. PLoS One Research Article Transcriptomic studies help to further our understanding of gene function. Human transcriptomic studies tend to focus on a particular subset of tissue types or a particular disease state; however, it is possible to collate into a compendium multiple studies that have been profiled using the same expression analysis platform to provide an overview of gene expression levels in many different tissues or under different conditions. In order to increase the knowledge and understanding we gain from such studies, intuitive visualization of gene expression data in such a compendium can be useful. The Human eFP (“electronic Fluorescent Pictograph”) Browser presented here is a tool for intuitive visualization of large human gene expression data sets on pictographic representations of the human body as gene expression “anatograms”. Pictographic representations for new data sets may be generated easily. The Human eFP Browser can also serve as a portal to other gene-specific information through link-outs to various online resources. Public Library of Science 2016-03-08 /pmc/articles/PMC4783024/ /pubmed/26954504 http://dx.doi.org/10.1371/journal.pone.0150982 Text en © 2016 Patel et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Patel, Rohan V. Hamanishi, Erin T. Provart, Nicholas J. A Human "eFP" Browser for Generating Gene Expression Anatograms |
title | A Human "eFP" Browser for Generating Gene Expression Anatograms |
title_full | A Human "eFP" Browser for Generating Gene Expression Anatograms |
title_fullStr | A Human "eFP" Browser for Generating Gene Expression Anatograms |
title_full_unstemmed | A Human "eFP" Browser for Generating Gene Expression Anatograms |
title_short | A Human "eFP" Browser for Generating Gene Expression Anatograms |
title_sort | human "efp" browser for generating gene expression anatograms |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783024/ https://www.ncbi.nlm.nih.gov/pubmed/26954504 http://dx.doi.org/10.1371/journal.pone.0150982 |
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