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A Human "eFP" Browser for Generating Gene Expression Anatograms

Transcriptomic studies help to further our understanding of gene function. Human transcriptomic studies tend to focus on a particular subset of tissue types or a particular disease state; however, it is possible to collate into a compendium multiple studies that have been profiled using the same exp...

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Detalles Bibliográficos
Autores principales: Patel, Rohan V., Hamanishi, Erin T., Provart, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783024/
https://www.ncbi.nlm.nih.gov/pubmed/26954504
http://dx.doi.org/10.1371/journal.pone.0150982
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author Patel, Rohan V.
Hamanishi, Erin T.
Provart, Nicholas J.
author_facet Patel, Rohan V.
Hamanishi, Erin T.
Provart, Nicholas J.
author_sort Patel, Rohan V.
collection PubMed
description Transcriptomic studies help to further our understanding of gene function. Human transcriptomic studies tend to focus on a particular subset of tissue types or a particular disease state; however, it is possible to collate into a compendium multiple studies that have been profiled using the same expression analysis platform to provide an overview of gene expression levels in many different tissues or under different conditions. In order to increase the knowledge and understanding we gain from such studies, intuitive visualization of gene expression data in such a compendium can be useful. The Human eFP (“electronic Fluorescent Pictograph”) Browser presented here is a tool for intuitive visualization of large human gene expression data sets on pictographic representations of the human body as gene expression “anatograms”. Pictographic representations for new data sets may be generated easily. The Human eFP Browser can also serve as a portal to other gene-specific information through link-outs to various online resources.
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spelling pubmed-47830242016-03-23 A Human "eFP" Browser for Generating Gene Expression Anatograms Patel, Rohan V. Hamanishi, Erin T. Provart, Nicholas J. PLoS One Research Article Transcriptomic studies help to further our understanding of gene function. Human transcriptomic studies tend to focus on a particular subset of tissue types or a particular disease state; however, it is possible to collate into a compendium multiple studies that have been profiled using the same expression analysis platform to provide an overview of gene expression levels in many different tissues or under different conditions. In order to increase the knowledge and understanding we gain from such studies, intuitive visualization of gene expression data in such a compendium can be useful. The Human eFP (“electronic Fluorescent Pictograph”) Browser presented here is a tool for intuitive visualization of large human gene expression data sets on pictographic representations of the human body as gene expression “anatograms”. Pictographic representations for new data sets may be generated easily. The Human eFP Browser can also serve as a portal to other gene-specific information through link-outs to various online resources. Public Library of Science 2016-03-08 /pmc/articles/PMC4783024/ /pubmed/26954504 http://dx.doi.org/10.1371/journal.pone.0150982 Text en © 2016 Patel et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Patel, Rohan V.
Hamanishi, Erin T.
Provart, Nicholas J.
A Human "eFP" Browser for Generating Gene Expression Anatograms
title A Human "eFP" Browser for Generating Gene Expression Anatograms
title_full A Human "eFP" Browser for Generating Gene Expression Anatograms
title_fullStr A Human "eFP" Browser for Generating Gene Expression Anatograms
title_full_unstemmed A Human "eFP" Browser for Generating Gene Expression Anatograms
title_short A Human "eFP" Browser for Generating Gene Expression Anatograms
title_sort human "efp" browser for generating gene expression anatograms
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783024/
https://www.ncbi.nlm.nih.gov/pubmed/26954504
http://dx.doi.org/10.1371/journal.pone.0150982
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