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Stoichiometry and Change of the mRNA Closed-Loop Factors as Translating Ribosomes Transit from Initiation to Elongation
Protein synthesis is a highly efficient process and is under exacting control. Yet, the actual abundance of translation factors present in translating complexes and how these abundances change during the transit of a ribosome across an mRNA remains unknown. Using analytical ultracentrifugation with...
Autores principales: | Wang, Xin, Xi, Wen, Toomey, Shaun, Chiang, Yueh-Chin, Hasek, Jiri, Laue, Thomas M., Denis, Clyde L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783044/ https://www.ncbi.nlm.nih.gov/pubmed/26953568 http://dx.doi.org/10.1371/journal.pone.0150616 |
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