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BIITE: A Tool to Determine HLA Class II Epitopes from T Cell ELISpot Data

Activation of CD4(+) T cells requires the recognition of peptides that are presented by HLA class II molecules and can be assessed experimentally using the ELISpot assay. However, even given an individual’s HLA class II genotype, identifying which class II molecule is responsible for a positive ELIS...

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Detalles Bibliográficos
Autores principales: Boelen, Lies, O’Neill, Patrick K., Quigley, Kathryn J., Reynolds, Catherine J., Maillere, Bernard, Robinson, John H., Lertmemongkolchai, Ganjana, Altmann, Daniel M., Boyton, Rosemary J., Asquith, Becca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783075/
https://www.ncbi.nlm.nih.gov/pubmed/26953935
http://dx.doi.org/10.1371/journal.pcbi.1004796