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BIITE: A Tool to Determine HLA Class II Epitopes from T Cell ELISpot Data
Activation of CD4(+) T cells requires the recognition of peptides that are presented by HLA class II molecules and can be assessed experimentally using the ELISpot assay. However, even given an individual’s HLA class II genotype, identifying which class II molecule is responsible for a positive ELIS...
Autores principales: | Boelen, Lies, O’Neill, Patrick K., Quigley, Kathryn J., Reynolds, Catherine J., Maillere, Bernard, Robinson, John H., Lertmemongkolchai, Ganjana, Altmann, Daniel M., Boyton, Rosemary J., Asquith, Becca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783075/ https://www.ncbi.nlm.nih.gov/pubmed/26953935 http://dx.doi.org/10.1371/journal.pcbi.1004796 |
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