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Medication overuse headache in Europe and Latin America: general demographic and clinical characteristics, referral pathways and national distribution of painkillers in a descriptive, multinational, multicenter study
BACKGROUND: Medication overuse headache (MOH) is a very disabling and costly disorder due to indirect costs, medication and healthcare utilization. The aim of the study was to describe general demographic and clinical characteristics of MOH, along with the national referral pathways and national pai...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Milan
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783306/ https://www.ncbi.nlm.nih.gov/pubmed/26957090 http://dx.doi.org/10.1186/s10194-016-0612-2 |
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author | Find, Ninett Louise Terlizzi, Rossana Munksgaard, Signe Bruun Bendtsen, Lars Tassorelli, Cristina Nappi, Giuseppe Katsarava, Zaza Lainez, Miguel Goicochea, Maria Teresa Shand, Beatriz Fadic, Ricardo Spadafora, Santiago Pagani, Marco Jensen, Rigmor |
author_facet | Find, Ninett Louise Terlizzi, Rossana Munksgaard, Signe Bruun Bendtsen, Lars Tassorelli, Cristina Nappi, Giuseppe Katsarava, Zaza Lainez, Miguel Goicochea, Maria Teresa Shand, Beatriz Fadic, Ricardo Spadafora, Santiago Pagani, Marco Jensen, Rigmor |
author_sort | Find, Ninett Louise |
collection | PubMed |
description | BACKGROUND: Medication overuse headache (MOH) is a very disabling and costly disorder due to indirect costs, medication and healthcare utilization. The aim of the study was to describe general demographic and clinical characteristics of MOH, along with the national referral pathways and national painkillers distribution in several European and Latin American (LA) Countries. METHODS: This descriptive cross-sectional observational study included 669 patients with MOH referred to headache-centers in Europe and LA as a part of the COMOESTAS project. Information about acute medication and healthcare utilization were collected by extensive questionnaires, supplemented with structured patient interviews. RESULTS: Triptans were overused by 31 % European patients and by 6 % in LA (p < 0.001), whereas ergotamines were overused by 4 % in Europe and 72 % in LA (p < 0.001). Simple analgesics were overused by 54 % in Europe and by 33 % in LA (p < 0.001), while combination-analgesics were more equally overused (24 % in Europe and 29 % in LA). More European patients (57 %) compared with LA patients (27 %) visited general practitioners (p < 0.001), and 83 % of European patients compared to 38 % in LA consulted headache specialists (p < 0.001). A total of 20 % in Europe and 30 % in LA visited emergency rooms (p = 0.007). CONCLUSION: There are marked variations between LA and Europe in healthcare pathways and in acute medication overuse regarding patients with MOH. This should be considered when planning prevention campaigns against MOH. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s10194-016-0612-2) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-4783306 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Springer Milan |
record_format | MEDLINE/PubMed |
spelling | pubmed-47833062016-04-09 Medication overuse headache in Europe and Latin America: general demographic and clinical characteristics, referral pathways and national distribution of painkillers in a descriptive, multinational, multicenter study Find, Ninett Louise Terlizzi, Rossana Munksgaard, Signe Bruun Bendtsen, Lars Tassorelli, Cristina Nappi, Giuseppe Katsarava, Zaza Lainez, Miguel Goicochea, Maria Teresa Shand, Beatriz Fadic, Ricardo Spadafora, Santiago Pagani, Marco Jensen, Rigmor J Headache Pain Research Article BACKGROUND: Medication overuse headache (MOH) is a very disabling and costly disorder due to indirect costs, medication and healthcare utilization. The aim of the study was to describe general demographic and clinical characteristics of MOH, along with the national referral pathways and national painkillers distribution in several European and Latin American (LA) Countries. METHODS: This descriptive cross-sectional observational study included 669 patients with MOH referred to headache-centers in Europe and LA as a part of the COMOESTAS project. Information about acute medication and healthcare utilization were collected by extensive questionnaires, supplemented with structured patient interviews. RESULTS: Triptans were overused by 31 % European patients and by 6 % in LA (p < 0.001), whereas ergotamines were overused by 4 % in Europe and 72 % in LA (p < 0.001). Simple analgesics were overused by 54 % in Europe and by 33 % in LA (p < 0.001), while combination-analgesics were more equally overused (24 % in Europe and 29 % in LA). More European patients (57 %) compared with LA patients (27 %) visited general practitioners (p < 0.001), and 83 % of European patients compared to 38 % in LA consulted headache specialists (p < 0.001). A total of 20 % in Europe and 30 % in LA visited emergency rooms (p = 0.007). CONCLUSION: There are marked variations between LA and Europe in healthcare pathways and in acute medication overuse regarding patients with MOH. This should be considered when planning prevention campaigns against MOH. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s10194-016-0612-2) contains supplementary material, which is available to authorized users. Springer Milan 2016-03-08 /pmc/articles/PMC4783306/ /pubmed/26957090 http://dx.doi.org/10.1186/s10194-016-0612-2 Text en © Find et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Research Article Find, Ninett Louise Terlizzi, Rossana Munksgaard, Signe Bruun Bendtsen, Lars Tassorelli, Cristina Nappi, Giuseppe Katsarava, Zaza Lainez, Miguel Goicochea, Maria Teresa Shand, Beatriz Fadic, Ricardo Spadafora, Santiago Pagani, Marco Jensen, Rigmor Medication overuse headache in Europe and Latin America: general demographic and clinical characteristics, referral pathways and national distribution of painkillers in a descriptive, multinational, multicenter study |
title | Medication overuse headache in Europe and Latin America: general demographic and clinical characteristics, referral pathways and national distribution of painkillers in a descriptive, multinational, multicenter study |
title_full | Medication overuse headache in Europe and Latin America: general demographic and clinical characteristics, referral pathways and national distribution of painkillers in a descriptive, multinational, multicenter study |
title_fullStr | Medication overuse headache in Europe and Latin America: general demographic and clinical characteristics, referral pathways and national distribution of painkillers in a descriptive, multinational, multicenter study |
title_full_unstemmed | Medication overuse headache in Europe and Latin America: general demographic and clinical characteristics, referral pathways and national distribution of painkillers in a descriptive, multinational, multicenter study |
title_short | Medication overuse headache in Europe and Latin America: general demographic and clinical characteristics, referral pathways and national distribution of painkillers in a descriptive, multinational, multicenter study |
title_sort | medication overuse headache in europe and latin america: general demographic and clinical characteristics, referral pathways and national distribution of painkillers in a descriptive, multinational, multicenter study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783306/ https://www.ncbi.nlm.nih.gov/pubmed/26957090 http://dx.doi.org/10.1186/s10194-016-0612-2 |
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