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Global genome splicing analysis reveals an increased number of alternatively spliced genes with aging
Alternative splicing (AS) is a key regulatory mechanism for the development of different tissues; however, not much is known about changes to alternative splicing during aging. Splicing events may become more frequent and widespread genome‐wide as tissues age and the splicing machinery stringency de...
Autores principales: | Rodríguez, Sofía A., Grochová, Diana, McKenna, Tomás, Borate, Bhavesh, Trivedi, Niraj S., Erdos, Michael R., Eriksson, Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783335/ https://www.ncbi.nlm.nih.gov/pubmed/26685868 http://dx.doi.org/10.1111/acel.12433 |
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