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A network pharmacology approach reveals new candidate caloric restriction mimetics in C. elegans

Caloric restriction (CR), a reduction in calorie intake without malnutrition, retards aging in several animal models from worms to mammals. Developing CR mimetics, compounds that reproduce the longevity benefits of CR without its side effects, is of widespread interest. Here, we employed the Connect...

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Detalles Bibliográficos
Autores principales: Calvert, Shaun, Tacutu, Robi, Sharifi, Samim, Teixeira, Rute, Ghosh, Pratul, de Magalhães, João Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783339/
https://www.ncbi.nlm.nih.gov/pubmed/26676933
http://dx.doi.org/10.1111/acel.12432

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