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A network pharmacology approach reveals new candidate caloric restriction mimetics in C. elegans
Caloric restriction (CR), a reduction in calorie intake without malnutrition, retards aging in several animal models from worms to mammals. Developing CR mimetics, compounds that reproduce the longevity benefits of CR without its side effects, is of widespread interest. Here, we employed the Connect...
Autores principales: | Calvert, Shaun, Tacutu, Robi, Sharifi, Samim, Teixeira, Rute, Ghosh, Pratul, de Magalhães, João Pedro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783339/ https://www.ncbi.nlm.nih.gov/pubmed/26676933 http://dx.doi.org/10.1111/acel.12432 |
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