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Characterization of age‐associated exhausted CD8(+) T cells defined by increased expression of Tim‐3 and PD‐1

Aging is accompanied by altered T‐cell responses that result in susceptibility to various diseases. Previous findings on the increased expression of inhibitory receptors, such as programmed cell death protein 1 (PD‐1), in the T cells of aged mice emphasize the importance of investigations into the r...

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Detalles Bibliográficos
Autores principales:	Lee, Kyoo‐A, Shin, Kwang‐Soo, Kim, Ga‐Young, Song, You Chan, Bae, Eun‐Ah, Kim, Il‐Kyu, Koh, Choong‐Hyun, Kang, Chang‐Yuil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783346/ https://www.ncbi.nlm.nih.gov/pubmed/26750587 http://dx.doi.org/10.1111/acel.12435

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